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To be able to ideal meet up with client's needs, all of our operations are strictly performed in line with our motto "High High-quality, Competitive Cost, Fast Service" for Lapatinib Powder Pruity 99%,Lapatinib Raw Materical,Lapatinib Ditosylate Salt. All products come with good quality and perfect after-sales services. Market-oriented and customer-oriented are what we have been being after. Sincerely look forward to Win-Win cooperation !
Product Name: Lapatinib
CAS NO.: 231277-92-2
Molecular Formula: C29H26ClFN4O4S
Molecular Weight: 581.0575432
Description: White crystal or crystalline powder
Chemical names, synonyms: Lapatinib(TINIBS), Lapatinib free base, GSK572016, GW 57201, Lapatinib(ditosylate salt), Lapatinib ditosylate
Minimum purity: 99%
Lapatinib is a synthetic, orally-active quinazoline with potential antineoplastic activity. Lapatinib reversibly blocks phosphorylation of the epidermal growth factor receptor (EGFR), ErbB2, and the Erk-1 and-2 and AKT kinases; it also inhibits cyclin D protein levels in human tumor cell lines and xenografts. EGFR and ErbB2 have been implicated in the growth of various tumor types. Check for active clinical trials or closed clinical trials using this agent.
Lapatinib is an anti-cancer drug developed by GlaxoSmithKline (GSK) as a treatment for solid tumours such as breast and lung cancer. It was approved by the FDA on March 13, 2007, for use in patients with advanced metastatic breast cancer in conjunction with the chemotherapy drug Capecitabine. Lapatinib is human epidermal growth factor receptor type 2 (HER2/ERBB2) and epidermal growth factor receptor (HER1/EGFR/ERBB1) tyrosine kinases inhibitor. It binds to the intracellular phosphorylation domain to prevent receptor autophosphorylation upon ligand binding.
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