• <listing id="vvvzt"></listing>
    <code id="vvvzt"></code>

    1. <code id="vvvzt"></code><small id="vvvzt"><delect id="vvvzt"></delect></small>
    2. <output id="vvvzt"></output>
      <code id="vvvzt"></code>
            <tt id="vvvzt"><noframes id="vvvzt"></noframes></tt>
              1. <listing id="vvvzt"></listing>

              2. <mark id="vvvzt"><button id="vvvzt"></button></mark>

              3. <tt id="vvvzt"><button id="vvvzt"><td id="vvvzt"></td></button></tt>

                <label id="vvvzt"></label>
                  <label id="vvvzt"></label>
                      <code id="vvvzt"></code>
                    1. <output id="vvvzt"><video id="vvvzt"></video></output>
                    2. <tt id="vvvzt"><button id="vvvzt"><address id="vvvzt"></address></button></tt>

                          1. http://www.tyds.icu
                            Home > Products > Intermediates > Ibrutinib Intermediates > Ibrutinib Intermediate Cas 1022150-12-4

                            Ibrutinib Intermediate Cas 1022150-12-4

                            Product Description

                            Chemical Name: 3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyriMidin-4-ylaMine
                            Molecular Formula: C22H22N6O
                            Formula Weight: 386.44968
                            CAS No.: 1022150-12-4

                            1022150-12-4


                            Ibrutinib is an orally bioavailable, small-molecule inhibitor of Bruton's tyrosine kinase (BTK) with potential antineoplastic activity. Upon oral administration, ibrutinib binds to and irreversibly inhibits BTK activity, thereby preventing both B-cell activation and B-cell-mediated signaling. This leads to an inhibition of the growth of malignant B cells that overexpress BTK. BTK, a member of the src-related BTK/Tec family of cytoplasmic tyrosine kinases, is required for B cell receptor signaling, plays a key role in B-cell maturation, and is overexpressed in a number of B-cell malignancies. The expression of BTK in tumor cells is also associated with increased proliferation and survival.


                            Looking for ideal Btk Inhibitor 1 R EnantioMer Intermeidate Manufacturer & supplier ? We have a wide selection at great prices to help you get creative. All the Ibrutinib N-1 Ingredient 99% are quality guaranteed. We are China Origin Factory of Targeted Covalent Drug Powder. If you have any question, please feel free to contact us.

                            Product Categories : Intermediates > Ibrutinib Intermediates

                            Email to this supplier
                            • *Subject:
                            • *Messages:
                              Your message must be between 20-8000 characters
                            Communicate with Supplier?Supplier
                            Mr. Vid Mr. Mr. Vid
                            What can I do for you?
                            Contact Supplier
                            浙江快乐彩走势图快乐12基本走势图
                          2. <listing id="vvvzt"></listing>
                            <code id="vvvzt"></code>

                            1. <code id="vvvzt"></code><small id="vvvzt"><delect id="vvvzt"></delect></small>
                            2. <output id="vvvzt"></output>
                              <code id="vvvzt"></code>
                                    <tt id="vvvzt"><noframes id="vvvzt"></noframes></tt>
                                      1. <listing id="vvvzt"></listing>

                                      2. <mark id="vvvzt"><button id="vvvzt"></button></mark>

                                      3. <tt id="vvvzt"><button id="vvvzt"><td id="vvvzt"></td></button></tt>

                                        <label id="vvvzt"></label>
                                          <label id="vvvzt"></label>
                                              <code id="vvvzt"></code>
                                            1. <output id="vvvzt"><video id="vvvzt"></video></output>
                                            2. <tt id="vvvzt"><button id="vvvzt"><address id="vvvzt"></address></button></tt>

                                                  1. <listing id="vvvzt"></listing>
                                                    <code id="vvvzt"></code>

                                                    1. <code id="vvvzt"></code><small id="vvvzt"><delect id="vvvzt"></delect></small>
                                                    2. <output id="vvvzt"></output>
                                                      <code id="vvvzt"></code>
                                                            <tt id="vvvzt"><noframes id="vvvzt"></noframes></tt>
                                                              1. <listing id="vvvzt"></listing>

                                                              2. <mark id="vvvzt"><button id="vvvzt"></button></mark>

                                                              3. <tt id="vvvzt"><button id="vvvzt"><td id="vvvzt"></td></button></tt>

                                                                <label id="vvvzt"></label>
                                                                  <label id="vvvzt"></label>
                                                                      <code id="vvvzt"></code>
                                                                    1. <output id="vvvzt"><video id="vvvzt"></video></output>
                                                                    2. <tt id="vvvzt"><button id="vvvzt"><address id="vvvzt"></address></button></tt>

                                                                          1. 江苏快三大小单双和值 买马46开奖结果 重庆时时彩走势图 有谁购买作弊器被骗了 北京赛pk10apk 浙江快乐12任4 四川金7乐昨日开奖结果 pk10有什么方法平刷 贵州体彩十一选最大遗漏值 江西时时彩开奖时间 重庆时时走势图诀窍 香港公司注册tm pk10高手技术分享 叮叮棋牌从哪下载 广东快乐10分走势图表 北京pk计划怎么看