Chemical Name: Fluconazole
Molecular Formula: C13H12F2N6O
Formula Weight: 306.27
CAS No.: 86386-73-4
It appears as white to yellow-white crystalline powder and is slightly smelly with bitter taste. It is easily soluble in glacial acetic acid, methanol or ethanol, hardly soluble in water and almost insoluble in ether with the melting point being 137~141.6 ℃, or melting point being 138~140 ℃ (derived from ethyl acetate-hexane).
This product belongs to fluorinated triazole antifungal drug with the antifungal spectrum being similar as ketoconazole but antifungal activity being higher than ketoconazole. Its mechanism of action is through inhibition of essential component of the fungal cell membrane, the ergosterol biosynthesis enzyme, blocking the ergosterol synthesis and breaking the integrity of the fungal cell wall, further inhibiting their growth and reproduction. Fluconazole oral tablet is available as both a generic and a brand-name drug. Brand name: Diflucan.
Fluconazole comes as a tablet or suspension you take by mouth. It also comes in an injectable form that can only be given to you by a healthcare provider.
Fluconazole oral tablet is used to prevent and treat candidiasis, a fungal infection. It`s also used to treat meningitis (infection of the brain or spinal cord, or both).
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