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                            Home > Products > Antidiabetic/Antihypertensive > Allopregnanolone Acetate Cas 906-83-2 Brexanolone

                            Allopregnanolone Acetate Cas 906-83-2 Brexanolone

                            Basic Info

                            Grade Standard: Medicine Grade

                            Type: Chemical Reagent

                            State: Solid

                            Volatile: Not Volatile

                            Product Description

                            Allopregnanolone, also known as 5α-pregnan-3α-ol-20-one or 3α,5α-tetrahydroprogesterone (3α,5α-THP), as well as brexanolone (USAN), is an endogenous inhibitory pregnane neurosteroid. It is synthesized from progesterone, and is a potent positive allosteric modulator of the action of γ-aminobutyric acid (GABA) at GABAA receptor. Allopregnanolone has effects similar to those of other positive allosteric modulators of the GABA action at GABAA receptor such as the . including anxiolytic, sedative, and anticonvulsant activity. Endogenously produced allopregnanolone exerts a pivotal neurophysiological role by fine-tuning of GABAA receptor and modulating the action of several positive allosteric modulators and agonists at GABAA receptor. The 21-hydroxylated derivative of this compound, tetrahydrodeoxycorticosterone (THDOC), is an endogenous inhibitory neurosteroid with similar properties to those of allopregnanolone, and the 3β-methyl analogue of allopregnanolone, ganaxolone, is under development to treat epilepsy and other conditions, including post-traumatic stress disorder (PTSD).



                            Chemical Name: ALLOPREGNANOLONE ACETATE

                            Molecular Formula: C23H36O3

                            Formula Weight: 360.53

                            CAS No.: 906-83-2







                            Looking for ideal Epiallopregnanolone Acetate Purity 99% Manufacturer & supplier ? We have a wide selection at great prices to help you get creative. All the Allopregnanolone Acetate Powder are quality guaranteed. We are China Origin Factory of Allopregnanolone Anxiety Gaba Obesity. If you have any question, please feel free to contact us.

                            Product Categories : Antidiabetic/Antihypertensive

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